Bedfont NObreath Nitric Oxide Monitor

Make better clinical decisions for patients with asthma.
 
From a single breath, the NObreath® can provide an indication whether there is inflammation present in the airways.
 
NICE recommends FeNO testing as an option to help diagnose and manage asthma in adults and children.1
 
The Bedfont® NObreath® is a simple to use handheld monitor that measures Fractional exhaled Nitric Oxide (FeNO) in the breath. The device has been designed for use within the primary care setting and can be used on children as well as adults.

An adult patient blows into the NObreath® for 12 seconds giving an instant result for FeNO in ppb (parts per billion).  The higher the FeNO reading the greater the inflammation in the airways.
 
 
Bedfont NOBreath FeNO Monitor in 90 Seconds...

 
 
 
 
 
How to use the Bedfont NOBreath FeNO Monitor

 

 
 
 
Benefits of using FeNO
 
  • FeNO measurement is recommended as an option to help diagnose asthma in adults and
    children1
     
  • Taking a measurement is non-invasive, quick and easy to perform3
     
  • Provides a complementary tool to other ways of assessing airways disease, including asthma.
     
  • Shows patient’s response to treatment, enabling the correct prescription of medication.
     
  • Aids in identifying patients who do/do not require ongoing treatment.4
     
  • Shown to be superior to the majority of conventional tests of lung function, such as peak flow recording and spirometry.3
 
 
 
Asthma and FeNO testing explained.
 
Currently, asthma diagnosis in clinical practice lacks a gold standard.1 Whilst Spirometry and provocation testing methods are widely used in asthma assessments, these tests only really show a partial picture as they are indirectly associated with airway inflammation.2 Spirometry and peak flow measurement also rely heavily on patient compliance and the need for a good quality spirometry test.
 
Results from spirometry and peak flow tests can effectively show that a patient has an obstruction, however conditions such as COPD or chronic cough may present symptoms that are similar to that found in asthma.5 Consequently this could lead to patients either being mis-diagnosed or not receiving the right treatment for the disease.6

In an asthmatic person, the bronchial tubes in the airways become inflamed. Nitric Oxide in the bronchial tubes is produced at a higher than normal concentration. This is exhaled on the breath and can be measured using a Fractional exhaled Nitric Oxide (FeNO) monitor. A FeNO test is simple to perform and requires very little respiratory effort by the patient. Results are displayed as a single value in ppb (parts per billion).7,8

The measurement of FeNO can be used as a non-invasive biomarker of airway inflammation in asthma sufferers. A positive FeNO reading in conjunction with spirometry and peak flow tests can help confirm a diagnosis of asthma in a patient and/or support ongoing treatment for the disease.8
 

 

Bibliography
1. Measuring fractional exhaled nitric oxide concentration in asthma. Diagnostics guidance. NICE. DG12. Published 2 April 2014
2. An Official ATS Clinical Practice Guideline: Interpretatoin of Exhaled Nitric Oxide Levels (FeNO) for Clinical Applications. Am J Respir Crit Care Med Vol 184. pp 602-615, 2011.
3. Andrew D. Smith, Jan O. Cowan, Sue Filsell, Chris MacLachlan, Gabrielle Monti-Sheehan, Pamela Jackson and D. Robin Taylor. Diagnosing Asthma: Comparisons between Exhaled Nitric Oxide Measurements and Conventional Tests. Am J Respir Crit Care Med Vol 169. pp 473-478, 2004.
4. D R Taylor, MW Pinenburg, A D Smith and J C D Jongste. Exhaled nitric oxide measurements: clinical application and interpretation. Thorax 2006;61:817-827.
5. P R. Airway inflammation in patients with symptoms suggesting asthma but with normal lung function [Internet]. ERS Journal. 2017 [cited 27 March 2017]. Available from: http://erj.ersjournals.com/content/erj/16/5/824.1.full.pdf
6. David T. Misdiagnosis of COPD and Asthma in Primary Care Patients 40 Years of Age and Over: Journal of Asthma: Vol 43, No 1 [Internet]. Tandfonline.com. 2017 [cited 27 March 2017].
Available from: http://www.tandfonline.com/doi/abs/10.1080/02770900500448738
7. Feng X. Fractional Exhaled Nitric Oxide in Relation to Asthma, Allergic Rhinitis, and Atopic Dermatitis in Chinese Children: Journal of Asthma: Vol 48, No 10 [Internet]. Tandfonline.com. 2017 [cited 27 March 2017].
Available from: http://www.tandfonline.com/doi/abs/10.3109/02770903.2011.627487
8. Ricciardolo F. Multiple roles of nitric oxide in the airways [Internet]. Multiple roles of nitric oxide in the airways. 2017 [cited 27 March 2017].
Available from: http://thorax.bmj.com/content/58/2/175.info